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Exploiting ancestral mammalian genomes for the prediction of human transcription factor binding sites

Overview of attention for article published in BMC Bioinformatics, December 2012
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Mentioned by

wikipedia
1 Wikipedia page

Citations

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1 Dimensions

Readers on

mendeley
12 Mendeley
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2 CiteULike
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Title
Exploiting ancestral mammalian genomes for the prediction of human transcription factor binding sites
Published in
BMC Bioinformatics, December 2012
DOI 10.1186/1471-2105-13-s19-s2
Pubmed ID
Authors

Mathieu Blanchette

Abstract

The computational prediction of Transcription Factor Binding Sites (TFBS) remains a challenge due to their short length and low information content. Comparative genomics approaches that simultaneously consider several related species and favor sites that have been conserved throughout evolution improve the accuracy (specificity) of the predictions but are limited due to a phenomenon called binding site turnover, where sequence evolution causes one TFBS to replace another in the same region. In parallel to this development, an increasing number of mammalian genomes are now sequenced and it is becoming possible to infer, to a surprisingly high degree of accuracy, ancestral mammalian sequences.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 8%
Unknown 11 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 33%
Student > Ph. D. Student 3 25%
Student > Master 2 17%
Student > Doctoral Student 1 8%
Professor > Associate Professor 1 8%
Other 0 0%
Unknown 1 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 58%
Biochemistry, Genetics and Molecular Biology 3 25%
Medicine and Dentistry 1 8%
Unknown 1 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2016.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from BMC Bioinformatics
#3,023
of 7,280 outputs
Outputs of similar age
#83,792
of 280,448 outputs
Outputs of similar age from BMC Bioinformatics
#58
of 137 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,280 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,448 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.