Title |
The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder
|
---|---|
Published in |
BMC Psychiatry, November 2010
|
DOI | 10.1186/1471-244x-10-99 |
Pubmed ID | |
Authors |
Tina B Lonsdorf, Christian Rück, Jan Bergström, Gerhard Andersson, Arne Öhman, Nils Lindefors, Martin Schalling |
Abstract |
Cognitive behavioral therapy (CBT) represents a learning process leading to symptom relief and resulting in long-term changes in behavior. CBT for panic disorder is based on exposure and exposure-based processes can be studied in the laboratory as extinction of experimentally acquired fear responses. We have recently demonstrated that the ability to extinguish learned fear responses is associated with a functional genetic polymorphism (COMTval158met) in the COMT gene and this study was aimed at transferring the experimental results on the COMTval158met polymorphism on extinction into a clinical setting. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 2 | 1% |
United Kingdom | 1 | <1% |
Denmark | 1 | <1% |
Norway | 1 | <1% |
Unknown | 142 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 29 | 20% |
Researcher | 21 | 14% |
Student > Bachelor | 17 | 12% |
Student > Master | 16 | 11% |
Student > Doctoral Student | 11 | 7% |
Other | 28 | 19% |
Unknown | 25 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 56 | 38% |
Medicine and Dentistry | 22 | 15% |
Neuroscience | 10 | 7% |
Agricultural and Biological Sciences | 8 | 5% |
Nursing and Health Professions | 6 | 4% |
Other | 13 | 9% |
Unknown | 32 | 22% |