You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Title |
Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1
|
|---|---|
| Published in |
BMC Biology, May 2011
|
| DOI | 10.1186/1741-7007-9-33 |
| Pubmed ID | |
| Authors |
Tara A Gomez, Natalie Kolawa, Marvin Gee, Michael J Sweredoski, Raymond J Deshaies |
| Abstract |
The proteasome is a multi-subunit protein machine that is the final destination for cellular proteins that have been marked for degradation via an ubiquitin (Ub) chain appendage. These ubiquitylated proteins either bind directly to the intrinsic proteasome ubiqutin chain receptors Rpn10, Rpn13, or Rpt5, or are shuttled to the proteasome by Rad23, Dsk2, or Ddi1. The latter proteins share an Ub association domain (UBA) for binding poly-Ub chains and an Ub-like-domain (UBL) for binding to the proteasome. It has been proposed that shuttling receptors dock on the proteasome via Rpn1, but the precise nature of the docking site remains poorly defined. |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Unknown | 75 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 36% |
| Researcher | 10 | 13% |
| Student > Master | 10 | 13% |
| Student > Bachelor | 7 | 9% |
| Student > Doctoral Student | 6 | 8% |
| Other | 9 | 12% |
| Unknown | 7 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 47% |
| Biochemistry, Genetics and Molecular Biology | 21 | 27% |
| Chemistry | 4 | 5% |
| Medicine and Dentistry | 3 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 1% |
| Other | 5 | 6% |
| Unknown | 7 | 9% |