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Mechanisms involved in breast cancer liver metastasis

Overview of attention for article published in Journal of Translational Medicine, February 2015
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2 X users

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185 Mendeley
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Title
Mechanisms involved in breast cancer liver metastasis
Published in
Journal of Translational Medicine, February 2015
DOI 10.1186/s12967-015-0425-0
Pubmed ID
Authors

Rui Ma, Yili Feng, Shuang Lin, Jiang Chen, Hui Lin, Xiao Liang, Heming Zheng, Xiujun Cai

Abstract

Liver metastasis is a frequent occurrence in patients with breast cancer; however, the available treatments are limited and ineffective. While liver-specific homing of breast cancer cells is an important feature of metastasis, the formation of liver metastases is not random. Indeed, breast cancer cell factors contribute to the liver microenvironment. Major breakthroughs have been achieved recently in understanding breast cancer liver metastasis (BCLM). The process of liver metastasis consists of multiple steps and involves various factors from breast cancer cells and the liver microenvironment. A further understanding of the roles of breast cancer cells and the liver microenvironment is crucial to guide future work in clinical treatments. In this review we discuss the contribution of breast cancer cells and the liver microenvironment to liver metastasis, with the aim to improve therapeutic efficacy for patients with BCLM.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
United States 1 <1%
Unknown 183 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 16%
Student > Bachelor 29 16%
Student > Master 25 14%
Researcher 20 11%
Student > Doctoral Student 9 5%
Other 16 9%
Unknown 57 31%
Readers by discipline Count As %
Medicine and Dentistry 43 23%
Biochemistry, Genetics and Molecular Biology 33 18%
Agricultural and Biological Sciences 20 11%
Engineering 6 3%
Chemistry 6 3%
Other 21 11%
Unknown 56 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2016.
All research outputs
#14,217,957
of 22,792,160 outputs
Outputs from Journal of Translational Medicine
#1,780
of 3,988 outputs
Outputs of similar age
#205,208
of 385,323 outputs
Outputs of similar age from Journal of Translational Medicine
#49
of 118 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,988 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 385,323 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.