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Subtelomeric multiplex ligation-dependent probe amplification as a supplement for rapid prenatal detection of fetal chromosomal aberrations

Overview of attention for article published in Molecular Cytogenetics, December 2014
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Mentioned by

peer_reviews
1 peer review site

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
11 Mendeley
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Title
Subtelomeric multiplex ligation-dependent probe amplification as a supplement for rapid prenatal detection of fetal chromosomal aberrations
Published in
Molecular Cytogenetics, December 2014
DOI 10.1186/s13039-014-0096-1
Pubmed ID
Authors

Xiangnan Chen, Huanzheng Li, Yijian Mao, Xueqin Xu, Jiaojiao Lv, Lili Zhou, Xiaoling Lin, Shaohua Tang

Abstract

Pregnant women with high-risk indications are highly suspected of fetal chromosomal aberrations. To determine whether Multiplex Ligation-dependent Probe Amplification (MLPA) using subtelomeric probe mixes (P036-E2 and P070-B2) is a reliable method for rapid detection of fetal chromosomal aberrations. The subtelomeric MLPA probe mixes were used to evaluate 50 blood samples from healthy individuals. 168 amniocytes and 182 umbilical cord blood samples from high-risk fetuses were analyzed using the same subtelomeric MLPA probe sets. Karyotyping was also performed in all cases of high-risk pregnancies, and single nucleotide polymorphism array analysis was used to confirm submicroscopic and ambiguous results from MLPA/karyotyping.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 27%
Student > Master 3 27%
Student > Doctoral Student 2 18%
Lecturer 1 9%
Professor > Associate Professor 1 9%
Other 0 0%
Unknown 1 9%
Readers by discipline Count As %
Medicine and Dentistry 4 36%
Biochemistry, Genetics and Molecular Biology 3 27%
Computer Science 1 9%
Nursing and Health Professions 1 9%
Unknown 2 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2015.
All research outputs
#15,325,004
of 22,792,160 outputs
Outputs from Molecular Cytogenetics
#154
of 400 outputs
Outputs of similar age
#213,907
of 361,118 outputs
Outputs of similar age from Molecular Cytogenetics
#10
of 24 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 400 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,118 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.