Title |
Sociogenomics of self vs. non-self cooperation during development of Dictyostelium discoideum
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Published in |
BMC Genomics, July 2014
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DOI | 10.1186/1471-2164-15-616 |
Pubmed ID | |
Authors |
Si I Li, Neil J Buttery, Christopher RL Thompson, Michael D Purugganan |
Abstract |
Dictyostelium discoideum, a microbial model for social evolution, is known to distinguish self from non-self and show genotype-dependent behavior during chimeric development. Aside from a small number of cell-cell recognition genes, however, little is known about the genetic basis of self/non-self recognition in this species. Based on the key hypothesis that there should be differential expression of genes if D. discoideum cells were interacting with non-clone mates, we performed transcriptomic profiling study in this species during clonal vs. chimeric development. The transcriptomic profiles of D. discoideum cells in clones vs. different chimeras were compared at five different developmental stages using a customized microarray. Effects of chimerism on global transcriptional patterns associated with social interactions were observed. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 4% |
Mexico | 1 | 4% |
Unknown | 23 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 24% |
Student > Master | 6 | 24% |
Researcher | 6 | 24% |
Student > Ph. D. Student | 4 | 16% |
Student > Doctoral Student | 1 | 4% |
Other | 1 | 4% |
Unknown | 1 | 4% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 13 | 52% |
Physics and Astronomy | 3 | 12% |
Biochemistry, Genetics and Molecular Biology | 3 | 12% |
Engineering | 2 | 8% |
Computer Science | 1 | 4% |
Other | 1 | 4% |
Unknown | 2 | 8% |