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Epidemiologic, clinical, diagnostic and therapeutic aspects of visceral leishmaniasis in renal transplant recipients: experience from thirty cases

Overview of attention for article published in BMC Infectious Diseases, February 2015
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Title
Epidemiologic, clinical, diagnostic and therapeutic aspects of visceral leishmaniasis in renal transplant recipients: experience from thirty cases
Published in
BMC Infectious Diseases, February 2015
DOI 10.1186/s12879-015-0852-9
Pubmed ID
Authors

Avelar Alves de Silva, Álvaro Pacheco E Silva Filho, Ricardio de Castro Cinta Sesso, Ronaldo de Matos Esmeraldo, Cláudia Maria Costa de Oliveira, Paula Frassinetti Castelo Branco Camurca Fernandes, Rodrigo Alves de Oliveira, Leila Silveira Veira de Silva, Valencio Pereira de Carvalho, Carlos Henrique Nery Costa, Jesusmar Ximenes Andrade, Diana Marisa Barros da Silva, Roosevelt Valente Chaves

Abstract

Visceral leishmaniasis is a disease caused by the protozoan Leishmania sp. and is transmitted by Lutzomyia longipalpis (sand fly). In renal transplant recipients, visceral leishmaniasis causes severe damage to the liver, spleen, and hematopoietic system, as well as poor outcomes for patients with transplanted kidneys. This study describes the largest series of cases of visceral leishmaniasis in renal transplant recipients, providing important information about the diagnostic routines and therapeutic strategies in this patient population. A retrospective, descriptive study was performed to analyze the distribution and evaluate the extent of the epidemiologic, clinical, diagnostic and therapeutic aspects of 30 renal transplant recipients from endemic regions who presented with visceral leishmaniasis in the post-transplantation period. In this study, visceral leishmaniasis was more frequent in men (80%). The mean age of presentation was 40 ± 10.5 years. The majority of patients worked in urban areas (66.7%), cohabitated with domestic animals (90%), and were from low-income households. In 73.3% of cases, diagnosis was made by direct isolation of Leishmania forms. Patients were treated with liposomal amphotericin, resulting in a high degree of disease remission (80%). This study describes the largest series of visceral leishmaniasis in renal transplant recipients and expands clinical-epidemiological knowledge for transplantation teams to perform adequate disease management for this specific patient population.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 15%
Student > Bachelor 7 15%
Student > Doctoral Student 5 11%
Other 5 11%
Professor 3 7%
Other 9 20%
Unknown 10 22%
Readers by discipline Count As %
Medicine and Dentistry 12 26%
Immunology and Microbiology 4 9%
Engineering 4 9%
Nursing and Health Professions 4 9%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 8 17%
Unknown 12 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2015.
All research outputs
#18,401,176
of 22,792,160 outputs
Outputs from BMC Infectious Diseases
#5,596
of 7,674 outputs
Outputs of similar age
#185,587
of 255,481 outputs
Outputs of similar age from BMC Infectious Diseases
#109
of 158 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,674 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,481 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.