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Neurally adjusted ventilatory assist and proportional assist ventilation both improve patient-ventilator interaction

Overview of attention for article published in Critical Care, December 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Average Attention Score compared to outputs of the same age and source

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16 X users
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2 Facebook pages

Citations

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73 Dimensions

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124 Mendeley
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Title
Neurally adjusted ventilatory assist and proportional assist ventilation both improve patient-ventilator interaction
Published in
Critical Care, December 2015
DOI 10.1186/s13054-015-0763-6
Pubmed ID
Authors

Matthieu Schmidt, Felix Kindler, Jérôme Cecchini, Tymothée Poitou, Elise Morawiec, Romain Persichini, Thomas Similowski, Alexandre Demoule

Abstract

The objective was to compare the impact of three assistance levels of different modes of mechanical ventilation; neurally adjusted ventilatory assist (NAVA), proportional assist ventilation (PAV), and pressure support ventilation (PSV) on major features of patient-ventilator interaction. PSV, NAVA, and PAV were set to obtain a tidal volume (VT) of 6 to 8 ml/kg (PSV100, NAVA100, and PAV100) in 16 intubated patients. Assistance was further decreased by 50% (PSV50, NAVA50, and PAV50) and then increased by 50% (PSV150, NAVA150, and PAV150) with all modes. The three modes were randomly applied. Airway flow and pressure, electrical activity of the diaphragm (EAdi), and blood gases were measured. VT, peak EAdi, coefficient of variation of VT and EAdi, and the prevalence of the main patient-ventilator asynchronies were calculated. PAV and NAVA prevented the increase of VT with high levels of assistance (median 7.4 (interquartile range (IQR) 5.7 to 10.1) ml/kg and 7.4 (IQR, 5.9 to 10.5) ml/kg with PAV150 and NAVA150 versus 10.9 (IQR, 8.9 to 12.0) ml/kg with PSV150, P <0.05). EAdi was higher with PAV than with PSV at level100 and level150. The coefficient of variation of VT was higher with NAVA and PAV (19 (IQR, 14 to 31)% and 21 (IQR 16 to 29)% with NAVA100 and PAV100 versus 13 (IQR 11 to 18)% with PSV100, P <0.05). The prevalence of ineffective triggering was lower with PAV and NAVA than with PSV (P <0.05), but the prevalence of double triggering was higher with NAVA than with PAV and PSV (P <0.05). PAV and NAVA both prevent overdistention, improve neuromechanical coupling, restore the variability of the breathing pattern, and decrease patient-ventilator asynchrony in fairly similar ways compared with PSV. Further studies are needed to evaluate the possible clinical benefits of NAVA and PAV on clinical outcomes. Clinicaltrials.gov NCT02056093 . Registered 18 December 2013.

X Demographics

X Demographics

The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Brazil 1 <1%
Unknown 122 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 15%
Other 16 13%
Student > Master 15 12%
Student > Bachelor 12 10%
Student > Ph. D. Student 10 8%
Other 27 22%
Unknown 26 21%
Readers by discipline Count As %
Medicine and Dentistry 70 56%
Nursing and Health Professions 12 10%
Engineering 8 6%
Materials Science 1 <1%
Biochemistry, Genetics and Molecular Biology 1 <1%
Other 0 0%
Unknown 32 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2020.
All research outputs
#3,681,116
of 24,976,442 outputs
Outputs from Critical Care
#2,822
of 6,490 outputs
Outputs of similar age
#60,273
of 399,282 outputs
Outputs of similar age from Critical Care
#281
of 546 outputs
Altmetric has tracked 24,976,442 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,490 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 399,282 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 546 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.