Title |
Expression of inhibitory regulators of innate immunity in patients with active tuberculosis
|
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Published in |
BMC Infectious Diseases, February 2015
|
DOI | 10.1186/s12879-015-0833-z |
Pubmed ID | |
Authors |
Dana C Blok, Liesbeth M Kager, Arie J Hoogendijk, Ivar O Lede, Wahid Rahman, Rumana Afroz, Paul Bresser, Jaring S van der Zee, Aniruddha Ghose, Caroline E Visser, Menno D de Jong, Abu Shahed Md Zahed, Md Anwar Husain, Khan Mashrequl Alam, Pravat Chandra Barua, Mahtabuddin Hassan, Ahmed Hossain, Md Abu Tayab, Rene Lutter, Nick Day, Arjen M Dondorp, Alex F de Vos, Cornelis van ’t Veer, Tom van der Poll |
Abstract |
Tuberculosis (TB) is an important cause of morbidity and mortality worldwide. Toll-like-receptors (TLRs) are important for the recognition of the causative agent Mycobacterium tuberculosis. Negative regulation of TLRs is necessary to control deleterious inflammatory damage, but could provide a means of immune evasion by M. tuberculosis as well. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Unknown | 61 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 18% |
Researcher | 10 | 16% |
Student > Bachelor | 10 | 16% |
Student > Ph. D. Student | 9 | 15% |
Student > Doctoral Student | 3 | 5% |
Other | 8 | 13% |
Unknown | 11 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 35% |
Immunology and Microbiology | 6 | 10% |
Biochemistry, Genetics and Molecular Biology | 5 | 8% |
Nursing and Health Professions | 5 | 8% |
Agricultural and Biological Sciences | 5 | 8% |
Other | 7 | 11% |
Unknown | 12 | 19% |