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X Demographics
Mendeley readers
Attention Score in Context
| Title |
CAG-encoded polyglutamine length polymorphism in the human genome
|
|---|---|
| Published in |
BMC Genomics, May 2007
|
| DOI | 10.1186/1471-2164-8-126 |
| Pubmed ID | |
| Authors |
Stefanie L Butland, Rebecca S Devon, Yong Huang, Carri-Lyn Mead, Alison M Meynert, Scott J Neal, Soo Sen Lee, Anna Wilkinson, George S Yang, Macaire MS Yuen, Michael R Hayden, Robert A Holt, Blair R Leavitt, BF Francis Ouellette |
| Abstract |
Expansion of polyglutamine-encoding CAG trinucleotide repeats has been identified as the pathogenic mutation in nine different genes associated with neurodegenerative disorders. The majority of individuals clinically diagnosed with spinocerebellar ataxia do not have mutations within known disease genes, and it is likely that additional ataxias or Huntington disease-like disorders will be found to be caused by this common mutational mechanism. We set out to determine the length distributions of CAG-polyglutamine tracts for the entire human genome in a set of healthy individuals in order to characterize the nature of polyglutamine repeat length variation across the human genome, to establish the background against which pathogenic repeat expansions can be detected, and to prioritize candidate genes for repeat expansion disorders. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Canada | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Norway | 1 | <1% |
| South Africa | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 94 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 25% |
| Researcher | 21 | 21% |
| Student > Master | 13 | 13% |
| Professor | 8 | 8% |
| Student > Bachelor | 8 | 8% |
| Other | 17 | 17% |
| Unknown | 10 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 39 | 38% |
| Biochemistry, Genetics and Molecular Biology | 26 | 25% |
| Medicine and Dentistry | 14 | 14% |
| Neuroscience | 6 | 6% |
| Unspecified | 2 | 2% |
| Other | 5 | 5% |
| Unknown | 10 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2019.
All research outputs
#4,828,366
of 25,390,970 outputs
Outputs from BMC Genomics
#1,876
of 11,239 outputs
Outputs of similar age
#14,182
of 82,856 outputs
Outputs of similar age from BMC Genomics
#5
of 37 outputs
Altmetric has tracked 25,390,970 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,239 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 82,856 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.