↓ Skip to main content

An improved kilogram-scale preparation of atorvastatin calcium

Overview of attention for article published in BMC Chemistry, February 2015
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
19 Dimensions

Readers on

mendeley
32 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
An improved kilogram-scale preparation of atorvastatin calcium
Published in
BMC Chemistry, February 2015
DOI 10.1186/s13065-015-0082-7
Pubmed ID
Authors

Yuri V Novozhilov, Mikhail V Dorogov, Maria V Blumina, Alexey V Smirnov, Mikhail Krasavin

Abstract

If literature protocols are followed, conversion of an advanced ketal ester intermediate (available in kilogram quantities via a published Paal-Knorr synthesis) to cholesterol-lowering drug atorvastatin calcium is hampered by several process issues, particularly at the final stage where the hemi-calcium salt is obtained.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 25%
Researcher 6 19%
Student > Ph. D. Student 4 13%
Student > Master 3 9%
Professor 1 3%
Other 2 6%
Unknown 8 25%
Readers by discipline Count As %
Chemistry 14 44%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Agricultural and Biological Sciences 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Chemical Engineering 1 3%
Other 2 6%
Unknown 9 28%