Title |
Proteomics-based metabolic modeling and characterization of the cellulolytic bacterium Thermobifida fusca
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Published in |
BMC Systems Biology, August 2014
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DOI | 10.1186/s12918-014-0086-2 |
Pubmed ID | |
Authors |
Niti Vanee, J Paul Brooks, Victor Spicer, Dmitriy Shamshurin, Oleg Krokhin, John A Wilkins, Yu Deng, Stephen S Fong |
Abstract |
Thermobifida fusca is a cellulolytic bacterium with potential to be used as a platform organism for sustainable industrial production of biofuels, pharmaceutical ingredients and other bioprocesses due to its capability of potential to convert plant biomass to value-added chemicals. To best develop T. fusca as a bioprocess organism, it is important to understand its native cellular processes. In the current study, we characterize the metabolic network of T. fusca through reconstruction of a genome-scale metabolic model and proteomics data. The overall goal of this study was to use multiple metabolic models generated by different methods and comparison to experimental data to gain a high-confidence understanding of the T. fusca metabolic network. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Singapore | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 47 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 13 | 27% |
Student > Ph. D. Student | 12 | 24% |
Student > Master | 7 | 14% |
Student > Doctoral Student | 3 | 6% |
Student > Bachelor | 2 | 4% |
Other | 3 | 6% |
Unknown | 9 | 18% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 17 | 35% |
Biochemistry, Genetics and Molecular Biology | 12 | 24% |
Environmental Science | 3 | 6% |
Chemical Engineering | 1 | 2% |
Computer Science | 1 | 2% |
Other | 4 | 8% |
Unknown | 11 | 22% |