Title |
Exploratory use of docetaxel loaded acid-prepared mesoporous spheres for the treatment of malignant melanoma
|
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Published in |
Cancer Nanotechnology, January 2015
|
DOI | 10.1186/s12645-015-0009-y |
Pubmed ID | |
Authors |
Sameer Kaiser, Maximilian B MacPherson, Ted A James, Albert Emery, Page Spiess, Albert van der Vliet, Christopher C Landry, Arti Shukla |
Abstract |
Five year survival for metastatic melanoma (MM) is very low at <10%. Therapeutic options have been limited secondary to systemic toxicity. As a result there has been a growing movement towards developing targeted drug delivery models. Prior research of this group has demonstrated the effectiveness of acid-prepared mesoporous spheres (APMS-TEG) in delivering chemotherapeutic agents at a lower effective dose than systemic administration. This study aims to assess the ability of the previously developed APMS-TEG particles to deliver therapeutic doses of docetaxel for the treatment of melanoma. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 2 | 20% |
Other | 1 | 10% |
Librarian | 1 | 10% |
Student > Master | 1 | 10% |
Student > Bachelor | 1 | 10% |
Other | 0 | 0% |
Unknown | 4 | 40% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 3 | 30% |
Biochemistry, Genetics and Molecular Biology | 1 | 10% |
Physics and Astronomy | 1 | 10% |
Unknown | 5 | 50% |