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Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus

Overview of attention for article published in Journal of Translational Medicine, January 2015
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Mentioned by

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3 tweeters

Citations

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7 Dimensions

Readers on

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21 Mendeley
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Title
Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus
Published in
Journal of Translational Medicine, January 2015
DOI 10.1186/s12967-015-0428-x
Pubmed ID
Authors

Maria Ascierto, Federica Bozzano, Davide Bedognetti, Francesco Marras, Cathy Schechterly, Kentaro Matsuura, Antonino Picciotto, Simona Marenco, Yingdong Zhao, Valeria DeGiorgi, Michele Sommariva, Lorenzo Moretta, Ena Wang, Harvey J Alter, Francesco M Marincola, Andrea De Maria

Abstract

Differences in the expression of Natural Killer cell receptors have been reported to reflect divergent clinical courses in patients with chronic infections or tumors. However, extensive molecular characterization at the transcriptional level to support this view is lacking. The aim of this work was to characterize baseline differences in purified NK cell transcriptional activity stratified by response to treatment with PEG-IFNα/RBV in patients chronically infected with HCV.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 33%
Student > Ph. D. Student 4 19%
Student > Master 2 10%
Other 1 5%
Student > Doctoral Student 1 5%
Other 2 10%
Unknown 4 19%
Readers by discipline Count As %
Medicine and Dentistry 7 33%
Agricultural and Biological Sciences 5 24%
Immunology and Microbiology 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Social Sciences 1 5%
Other 1 5%
Unknown 5 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2015.
All research outputs
#14,811,065
of 19,208,681 outputs
Outputs from Journal of Translational Medicine
#2,522
of 3,414 outputs
Outputs of similar age
#149,905
of 226,541 outputs
Outputs of similar age from Journal of Translational Medicine
#1
of 1 outputs
Altmetric has tracked 19,208,681 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,414 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,541 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them