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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Intravenous ascorbic acid to prevent and treat cancer-associated sepsis?
|
|---|---|
| Published in |
Journal of Translational Medicine, March 2011
|
| DOI | 10.1186/1479-5876-9-25 |
| Pubmed ID | |
| Authors |
Thomas E Ichim, Boris Minev, Todd Braciak, Brandon Luna, Ron Hunninghake, Nina A Mikirova, James A Jackson, Michael J Gonzalez, Jorge R Miranda-Massari, Doru T Alexandrescu, Constantin A Dasanu, Vladimir Bogin, Janis Ancans, R Brian Stevens, Boris Markosian, James Koropatnick, Chien-Shing Chen, Neil H Riordan |
| Abstract |
The history of ascorbic acid (AA) and cancer has been marked with controversy. Clinical studies evaluating AA in cancer outcome continue to the present day. However, the wealth of data suggesting that AA may be highly beneficial in addressing cancer-associated inflammation, particularly progression to systemic inflammatory response syndrome (SIRS) and multi organ failure (MOF), has been largely overlooked. Patients with advanced cancer are generally deficient in AA. Once these patients develop septic symptoms, a further decrease in ascorbic acid levels occurs. Given the known role of ascorbate in: a) maintaining endothelial and suppression of inflammatory markers; b) protection from sepsis in animal models; and c) direct antineoplastic effects, we propose the use of ascorbate as an adjuvant to existing modalities in the treatment and prevention of cancer-associated sepsis. |
X Demographics
The data shown below were collected from the profiles of 33 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 12 | 36% |
| United Kingdom | 2 | 6% |
| Ireland | 1 | 3% |
| Sweden | 1 | 3% |
| Mexico | 1 | 3% |
| Spain | 1 | 3% |
| Kenya | 1 | 3% |
| Peru | 1 | 3% |
| Italy | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 10 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 27 | 82% |
| Practitioners (doctors, other healthcare professionals) | 4 | 12% |
| Scientists | 2 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Portugal | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 92 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 18 | 19% |
| Researcher | 13 | 13% |
| Other | 11 | 11% |
| Student > Bachelor | 10 | 10% |
| Professor | 6 | 6% |
| Other | 27 | 28% |
| Unknown | 12 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 50 | 52% |
| Agricultural and Biological Sciences | 11 | 11% |
| Nursing and Health Professions | 5 | 5% |
| Immunology and Microbiology | 3 | 3% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Other | 13 | 13% |
| Unknown | 12 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2023.
All research outputs
#1,260,796
of 25,759,158 outputs
Outputs from Journal of Translational Medicine
#243
of 4,709 outputs
Outputs of similar age
#4,669
of 121,007 outputs
Outputs of similar age from Journal of Translational Medicine
#2
of 16 outputs
Altmetric has tracked 25,759,158 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,709 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,007 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.