Title |
Improvement of pain and regional osteoporotic changes in the foot and ankle by low-dose bisphosphonate therapy for complex regional pain syndrome type I: a case series
|
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Published in |
Journal of Medical Case Reports, August 2011
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DOI | 10.1186/1752-1947-5-349 |
Pubmed ID | |
Authors |
Yasuhisa Abe, Kousuke Iba, Junichi Takada, Takuro Wada, Toshihiko Yamashita |
Abstract |
Complex regional pain syndrome is characterized by pain, allodynia, hyperalgesia, edema, signs of vasomotor instability, movement disorders, joint stiffness, and regional osteopenia. It is recognized to be difficult to treat, despite various methods of treatment, including physiotherapy, calcitonin, corticosteroids, sympathetic blockade, and nonsteroidal anti-inflammatory drugs. Pathophysiologically, complex regional pain syndrome reveals enhanced regional bone resorption and high bone turnover, and so bisphosphonates, which have a potent inhibitory effect on bone resorption, were proposed for the treatment of complex regional pain syndrome. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 37 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 9 | 24% |
Student > Master | 4 | 11% |
Professor | 4 | 11% |
Student > Bachelor | 3 | 8% |
Student > Doctoral Student | 3 | 8% |
Other | 10 | 27% |
Unknown | 4 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 68% |
Nursing and Health Professions | 2 | 5% |
Neuroscience | 2 | 5% |
Agricultural and Biological Sciences | 1 | 3% |
Sports and Recreations | 1 | 3% |
Other | 1 | 3% |
Unknown | 5 | 14% |