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Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells

Overview of attention for article published in Environmental Health and Preventive Medicine, September 2011
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1 Facebook page

Citations

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36 Mendeley
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Title
Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells
Published in
Environmental Health and Preventive Medicine, September 2011
DOI 10.1007/s12199-011-0239-5
Pubmed ID
Authors

Noriyuki Nishimura, Tri Budi Hartomo, Thi Van Huyen Pham, Myeong Jin Lee, Tomoto Yamamoto, Satoru Morikawa, Daiichiro Hasegawa, Hiroki Takeda, Keiichiro Kawasaki, Yoshiyuki Kosaka, Nobuyuki Yamamoto, Ikuko Kubokawa, Takeshi Mori, Tomoko Yanai, Akira Hayakawa, Yasuhiro Takeshima, Kazumoto Iijima, Masafumi Matsuo, Hisahide Nishio

Abstract

A growing number of epidemiological studies have demonstrated that the consumption of green tea inhibits the growth of a variety of cancers. Epigallocatechin gallate (EGCG), the most abundant catechin in green tea, has been shown to have an anti-cancer effect against many cancers. Most cancers are believed to be initiated from and maintained by a small population of tumor-initiating cells (TICs) that are responsible for chemotherapeutic resistance and tumor relapse. In neuroblastoma, an aggressive pediatric tumor that often relapses and has a poor prognosis, TICs were recently identified as spheres grown in a serum-free non-adherent culture used for neural crest stem cell growth. Although EGCG has been reported to induce growth arrest and apoptosis in neuroblastoma cells, its effect on neuroblastoma TICs remains to be defined.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 22%
Student > Bachelor 5 14%
Student > Master 4 11%
Researcher 4 11%
Other 3 8%
Other 3 8%
Unknown 9 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 22%
Agricultural and Biological Sciences 6 17%
Medicine and Dentistry 6 17%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Unspecified 1 3%
Other 4 11%
Unknown 9 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2011.
All research outputs
#20,145,561
of 22,651,245 outputs
Outputs from Environmental Health and Preventive Medicine
#416
of 483 outputs
Outputs of similar age
#115,919
of 126,168 outputs
Outputs of similar age from Environmental Health and Preventive Medicine
#5
of 5 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 483 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 126,168 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.