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X Demographics
Mendeley readers
Attention Score in Context
| Title |
New horizons in tumor microenvironment biology: challenges and opportunities
|
|---|---|
| Published in |
BMC Medicine, March 2015
|
| DOI | 10.1186/s12916-015-0278-7 |
| Pubmed ID | |
| Authors |
Fei Chen, Xueqian Zhuang, Liangyu Lin, Pengfei Yu, Ying Wang, Yufang Shi, Guohong Hu, Yu Sun |
| Abstract |
The tumor microenvironment (TME) is being increasingly recognized as a key factor in multiple stages of disease progression, particularly local resistance, immune-escaping, and distant metastasis, thereby substantially impacting the future development of frontline interventions in clinical oncology. An appropriate understanding of the TME promotes evaluation and selection of candidate agents to control malignancies at both the primary sites as well as the metastatic settings. This review presents a timely outline of research advances in TME biology and highlights the prospect of targeting the TME as a critical strategy to overcome acquired resistance, prevent metastasis, and improve therapeutic efficacy. As benign cells in TME niches actively modulate response of cancer cells to a broad range of standard chemotherapies and targeted agents, cancer-oriented therapeutics should be combined with TME-targeting treatments to achieve optimal clinical outcomes. Overall, a body of updated information is delivered to summarize recently emerging and rapidly progressing aspects of TME studies, and to provide a significant guideline for prospective development of personalized medicine, with the long term aim of providing a cure for cancer patients. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 15% |
| Germany | 1 | 8% |
| Switzerland | 1 | 8% |
| Greece | 1 | 8% |
| Spain | 1 | 8% |
| United States | 1 | 8% |
| Australia | 1 | 8% |
| Mexico | 1 | 8% |
| Unknown | 4 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 54% |
| Scientists | 4 | 31% |
| Practitioners (doctors, other healthcare professionals) | 2 | 15% |
Mendeley readers
The data shown below were compiled from readership statistics for 577 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | <1% |
| Portugal | 1 | <1% |
| Colombia | 1 | <1% |
| Netherlands | 1 | <1% |
| Chile | 1 | <1% |
| Italy | 1 | <1% |
| Germany | 1 | <1% |
| Sweden | 1 | <1% |
| United Kingdom | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 565 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 111 | 19% |
| Student > Master | 86 | 15% |
| Researcher | 74 | 13% |
| Student > Bachelor | 68 | 12% |
| Student > Doctoral Student | 43 | 7% |
| Other | 67 | 12% |
| Unknown | 128 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 139 | 24% |
| Agricultural and Biological Sciences | 98 | 17% |
| Medicine and Dentistry | 70 | 12% |
| Immunology and Microbiology | 27 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 19 | 3% |
| Other | 76 | 13% |
| Unknown | 148 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 65. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2024.
All research outputs
#647,193
of 25,165,154 outputs
Outputs from BMC Medicine
#467
of 3,941 outputs
Outputs of similar age
#7,897
of 263,824 outputs
Outputs of similar age from BMC Medicine
#15
of 72 outputs
Altmetric has tracked 25,165,154 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,941 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.7. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,824 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.