↓ Skip to main content

A novel reporter of notch signalling indicates regulated and random notch activation during vertebrate neurogenesis

Overview of attention for article published in BMC Biology, August 2011
Altmetric Badge

Mentioned by

blogs
1 blog
facebook
1 Facebook page

Citations

dimensions_citation
39 Dimensions

Readers on

mendeley
126 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
A novel reporter of notch signalling indicates regulated and random notch activation during vertebrate neurogenesis
Published in
BMC Biology, August 2011
DOI 10.1186/1741-7007-9-58
Pubmed ID
Authors

Filipe Vilas-Boas, Rita Fior, Jason R Swedlow, Kate G Storey, Domingos Henrique

Abstract

Building the complex vertebrate nervous system involves the regulated production of neurons and glia while maintaining a progenitor cell population. Neurogenesis starts asynchronously in different regions of the embryo and occurs over a long period of time, allowing progenitor cells to be exposed to multiple extrinsic signals that regulate the production of different cell types. Notch-mediated cell-cell signalling is one of the mechanisms that maintain the progenitor pool, however, little is known about how the timing of Notch activation is related to the cell cycle and the distinct modes of cell division that generate neurons. An essential tool with which to investigate the role of Notch signalling on cell by cell basis is the development a faithful reporter of Notch activity.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 3 2%
United States 2 2%
United Kingdom 2 2%
Unknown 119 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 29%
Researcher 27 21%
Student > Master 12 10%
Student > Bachelor 10 8%
Professor > Associate Professor 6 5%
Other 18 14%
Unknown 17 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 64 51%
Biochemistry, Genetics and Molecular Biology 26 21%
Neuroscience 7 6%
Medicine and Dentistry 3 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 <1%
Other 6 5%
Unknown 19 15%