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Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics

Overview of attention for article published in BMC Cancer, September 2011
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Title
Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics
Published in
BMC Cancer, September 2011
DOI 10.1186/1471-2407-11-396
Pubmed ID
Authors

Hien Dang, Wei Ding, Dow Emerson, C Bart Rountree

Abstract

Tumor initiating stem-like cells (TISCs) are a subset of neoplastic cells that possess distinct survival mechanisms and self-renewal characteristics crucial for tumor maintenance and propagation. The induction of epithelial-mesenchymal-transition (EMT) by TGFβ has been recently linked to the acquisition of TISC characteristics in breast cancer. In HCC, a TISC and EMT phenotype correlates with a worse prognosis. In this work, our aim is to elucidate the underlying mechanism by which cells acquire tumor initiating characteristics after EMT.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
France 1 1%
Israel 1 1%
India 1 1%
Singapore 1 1%
Spain 1 1%
Greece 1 1%
United States 1 1%
Unknown 89 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 24%
Researcher 21 22%
Student > Master 12 12%
Student > Bachelor 7 7%
Professor > Associate Professor 7 7%
Other 13 13%
Unknown 14 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 38%
Medicine and Dentistry 21 22%
Biochemistry, Genetics and Molecular Biology 13 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Psychology 2 2%
Other 6 6%
Unknown 16 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2011.
All research outputs
#20,145,561
of 22,651,245 outputs
Outputs from BMC Cancer
#6,476
of 8,237 outputs
Outputs of similar age
#120,032
of 130,474 outputs
Outputs of similar age from BMC Cancer
#79
of 105 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,237 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,474 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.