Title |
Human and great ape red blood cells differ in plasmalogen levels and composition
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Published in |
Lipids in Health and Disease, June 2011
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DOI | 10.1186/1476-511x-10-101 |
Pubmed ID | |
Authors |
Ann B Moser, Steven J Steinberg, Paul A Watkins, Hugo W Moser, Krishna Ramaswamy, Kimberly D Siegmund, D Rick Lee, John J Ely, Oliver A Ryder, Joseph G Hacia |
Abstract |
Plasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as influence intracellular signaling and membrane dynamics. Plasmalogens are particularly enriched in cells and tissues of the human nervous, immune, and cardiovascular systems. Humans with severely reduced plasmalogen levels have reduced life spans, abnormal neurological development, skeletal dysplasia, impaired respiration, and cataracts. Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Uruguay | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 2% |
United Kingdom | 1 | 1% |
Kenya | 1 | 1% |
Unknown | 79 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 18 | 22% |
Student > Master | 13 | 16% |
Student > Bachelor | 13 | 16% |
Researcher | 10 | 12% |
Professor > Associate Professor | 7 | 8% |
Other | 10 | 12% |
Unknown | 12 | 14% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 19 | 23% |
Biochemistry, Genetics and Molecular Biology | 16 | 19% |
Medicine and Dentistry | 11 | 13% |
Chemistry | 10 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Other | 10 | 12% |
Unknown | 14 | 17% |