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Coma in fatal adult human malaria is not caused by cerebral oedema

Overview of attention for article published in Malaria Journal, September 2011
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Title
Coma in fatal adult human malaria is not caused by cerebral oedema
Published in
Malaria Journal, September 2011
DOI 10.1186/1475-2875-10-267
Pubmed ID
Authors

Isabelle M Medana, Nicholas PJ Day, Navakanit Sachanonta, Nguyen TH Mai, Arjen M Dondorp, Emsri Pongponratn, Tran T Hien, Nicholas J White, Gareth DH Turner

Abstract

The role of brain oedema in the pathophysiology of cerebral malaria is controversial. Coma associated with severe Plasmodium falciparum malaria is multifactorial, but associated with histological evidence of parasitized erythrocyte sequestration and resultant microvascular congestion in cerebral vessels. To determine whether these changes cause breakdown of the blood-brain barrier and resultant perivascular or parenchymal cerebral oedema, histology, immunohistochemistry and image analysis were used to define the prevalence of histological patterns of oedema and the expression of specific molecular pathways involved in water balance in the brain in adults with fatal falciparum malaria.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Denmark 1 1%
Pakistan 1 1%
Nigeria 1 1%
Unknown 90 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 22%
Researcher 16 17%
Student > Master 15 16%
Student > Bachelor 8 9%
Professor 5 5%
Other 16 17%
Unknown 13 14%
Readers by discipline Count As %
Medicine and Dentistry 28 30%
Agricultural and Biological Sciences 27 29%
Pharmacology, Toxicology and Pharmaceutical Science 7 7%
Immunology and Microbiology 5 5%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 8 9%
Unknown 15 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2012.
All research outputs
#17,646,807
of 22,651,245 outputs
Outputs from Malaria Journal
#4,817
of 5,533 outputs
Outputs of similar age
#106,419
of 130,159 outputs
Outputs of similar age from Malaria Journal
#57
of 62 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,533 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,159 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.