Title |
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
|
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Published in |
Genome Biology (Online Edition), January 2007
|
DOI | 10.1186/gb-2007-8-5-r76 |
Pubmed ID | |
Authors |
Jason I Herschkowitz, Karl Simin, Victor J Weigman, Igor Mikaelian, Jerry Usary, Zhiyuan Hu, Karen E Rasmussen, Laundette P Jones, Shahin Assefnia, Subhashini Chandrasekharan, Michael G Backlund, Yuzhi Yin, Andrey I Khramtsov, Roy Bastein, John Quackenbush, Robert I Glazer, Powel H Brown, Jeffrey E Green, Levy Kopelovich, Priscilla A Furth, Juan P Palazzo, Olufunmilayo I Olopade, Philip S Bernard, Gary A Churchill, Terry Van Dyke, Charles M Perou |
Abstract |
Although numerous mouse models of breast carcinomas have been developed, we do not know the extent to which any faithfully represent clinically significant human phenotypes. To address this need, we characterized mammary tumor gene expression profiles from 13 different murine models using DNA microarrays and compared the resulting data to those from human breast tumors. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 9 | 1% |
United Kingdom | 8 | <1% |
Germany | 3 | <1% |
Argentina | 2 | <1% |
France | 2 | <1% |
Canada | 2 | <1% |
India | 1 | <1% |
Pakistan | 1 | <1% |
Australia | 1 | <1% |
Other | 4 | <1% |
Unknown | 778 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 209 | 26% |
Researcher | 124 | 15% |
Student > Master | 109 | 13% |
Student > Bachelor | 78 | 10% |
Student > Doctoral Student | 49 | 6% |
Other | 133 | 16% |
Unknown | 109 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 274 | 34% |
Biochemistry, Genetics and Molecular Biology | 200 | 25% |
Medicine and Dentistry | 120 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 28 | 3% |
Chemistry | 12 | 1% |
Other | 51 | 6% |
Unknown | 126 | 16% |