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Attention Score in Context
Title |
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by Methyl-CpG binding proteins and histone modifications
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Published in |
BMC Cancer, June 2010
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DOI | 10.1186/1471-2407-10-297 |
Pubmed ID | |
Authors |
Imke Müller, Frank Wischnewski, Klaus Pantel, Heidi Schwarzenbach |
Abstract |
The aim of the current study was to analyze the involvement of methyl-CpG binding proteins (MBDs) and histone modifications on the regulation of CD44, Cyclin D2, GLIPR1 and PTEN in different cellular contexts such as the prostate cancer cells DU145 and LNCaP, and the breast cancer cells MCF-7. Since global chromatin changes have been shown to occur in tumours and regions of tumour-associated genes are affected by epigenetic modifications, these may constitute important regulatory mechanisms for the pathogenesis of malignant transformation. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
France | 1 | 1% |
Austria | 1 | 1% |
Unknown | 69 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 25% |
Student > Ph. D. Student | 17 | 24% |
Student > Postgraduate | 5 | 7% |
Student > Bachelor | 5 | 7% |
Student > Doctoral Student | 4 | 6% |
Other | 13 | 18% |
Unknown | 10 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 29 | 40% |
Biochemistry, Genetics and Molecular Biology | 11 | 15% |
Medicine and Dentistry | 7 | 10% |
Chemistry | 5 | 7% |
Engineering | 2 | 3% |
Other | 7 | 10% |
Unknown | 11 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2011.
All research outputs
#15,234,609
of 22,651,245 outputs
Outputs from BMC Cancer
#4,098
of 8,237 outputs
Outputs of similar age
#75,908
of 93,783 outputs
Outputs of similar age from BMC Cancer
#50
of 63 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,237 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 93,783 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.