Title |
An assessment of adverse drug reactions among HIV positive patients receiving antiretroviral treatment in South Africa
|
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Published in |
AIDS Research and Therapy, March 2015
|
DOI | 10.1186/s12981-015-0044-0 |
Pubmed ID | |
Authors |
Lieketseng J Masenyetse, Samuel OM Manda, Henry G Mwambi |
Abstract |
Antiretroviral treatment (ART) has been effective in reducing HIV/AIDS related morbidity and mortality. However, the use and uptake of ART has resulted in adverse reactions, due mainly to the medicine's toxicity and interactions with other medicines. The timing of adverse drug reactions (ADRs) among these patients is a critical public health issue for antiretroviral (ARV) treatment adherence and retention. Reliable monitoring of HIV patients on ART is through a structured pharmacovigilance surveillance system. However, recurrent nature of these data pose challenges in their analyses. This study aimed at modelling the timing of ADR events in HIV patients on ART using correlated time-to-event models. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 33% |
Unknown | 4 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 67% |
Practitioners (doctors, other healthcare professionals) | 2 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Denmark | 1 | <1% |
Unknown | 174 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 40 | 23% |
Student > Postgraduate | 23 | 13% |
Student > Bachelor | 23 | 13% |
Researcher | 16 | 9% |
Student > Ph. D. Student | 13 | 7% |
Other | 23 | 13% |
Unknown | 37 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 50 | 29% |
Pharmacology, Toxicology and Pharmaceutical Science | 31 | 18% |
Nursing and Health Professions | 14 | 8% |
Agricultural and Biological Sciences | 6 | 3% |
Immunology and Microbiology | 6 | 3% |
Other | 24 | 14% |
Unknown | 44 | 25% |