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Retroviral expression of human arginine decarboxylase reduces oxidative stress injury in mouse cortical astrocytes

Overview of attention for article published in BMC Neuroscience, August 2014
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Title
Retroviral expression of human arginine decarboxylase reduces oxidative stress injury in mouse cortical astrocytes
Published in
BMC Neuroscience, August 2014
DOI 10.1186/1471-2202-15-99
Pubmed ID
Authors

Samin Hong, Mi Ran Son, Kyungeun Yun, Won Taek Lee, Kyung Ah Park, Jong Eun Lee

Abstract

In physiologic and pathologic conditions of the central nervous system (CNS), astrocytes are a double-edged sword. They not only support neuronal homeostasis but also contribute to increases in neuronal demise. A large body of experimental evidence has shown that impaired astrocytes play crucial roles in the pathologic process of cerebral ischemia; therefore, astrocytes may represent a breakthrough target for neuroprotective therapeutic strategies. Agmatine, an endogenous polyamine catalyzed from L-arginine by arginine decarboxylase (ADC), is a neuromodulator and it protects neurons/glia against various injuries.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Romania 1 3%
Unknown 28 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 21%
Student > Ph. D. Student 4 14%
Student > Postgraduate 3 10%
Student > Master 3 10%
Student > Bachelor 2 7%
Other 3 10%
Unknown 8 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 24%
Medicine and Dentistry 5 17%
Nursing and Health Professions 2 7%
Neuroscience 2 7%
Sports and Recreations 1 3%
Other 3 10%
Unknown 9 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2015.
All research outputs
#20,264,045
of 22,794,367 outputs
Outputs from BMC Neuroscience
#1,054
of 1,244 outputs
Outputs of similar age
#198,161
of 236,404 outputs
Outputs of similar age from BMC Neuroscience
#32
of 33 outputs
Altmetric has tracked 22,794,367 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,244 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,404 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.