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Mendeley readers
Attention Score in Context
| Title |
A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer
|
|---|---|
| Published in |
BMC Cancer, May 2014
|
| DOI | 10.1186/1471-2407-14-352 |
| Pubmed ID | |
| Authors |
Nelma Pértega-Gomes, José R Vizcaíno, Jan Attig, Sarah Jurmeister, Carlos Lopes, Fátima Baltazar |
| Abstract |
In a malignant tumour, cancer cells are embedded in stromal cells, namely cancer-associated fibroblasts (CAFs). These CAFs are now accepted as important players in cancer dynamics, being involved in tumour growth and progression. Although there are various reports on the interaction between tumour and stromal cells, the clinico-pathological significance of this cross-talk is still largely unknown. In this study, we aimed to characterise the expression of key metabolic proteins involved in glucose transport, pyruvate/lactate shuttle system, glycolytic metabolism and fatty acid oxidation in CAFs and tumour cells in different stages of malignant transformation. We further aimed to contextualise the clinico-pathological significance of these protein expression profiles with reference to known prognostic indicators, including biochemical recurrence in pT stage. |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Romania | 1 | <1% |
| Unknown | 106 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 18% |
| Researcher | 18 | 17% |
| Student > Master | 14 | 13% |
| Student > Doctoral Student | 10 | 9% |
| Student > Bachelor | 10 | 9% |
| Other | 17 | 16% |
| Unknown | 19 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 22% |
| Biochemistry, Genetics and Molecular Biology | 23 | 21% |
| Agricultural and Biological Sciences | 19 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Physics and Astronomy | 3 | 3% |
| Other | 13 | 12% |
| Unknown | 22 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2015.
All research outputs
#20,264,045
of 22,794,367 outputs
Outputs from BMC Cancer
#6,488
of 8,295 outputs
Outputs of similar age
#192,040
of 226,424 outputs
Outputs of similar age from BMC Cancer
#116
of 127 outputs
Altmetric has tracked 22,794,367 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,295 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,424 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 127 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.