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Mendeley readers
Attention Score in Context
| Title |
Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment
|
|---|---|
| Published in |
Immunity & Ageing, March 2015
|
| DOI | 10.1186/s12979-015-0029-9 |
| Pubmed ID | |
| Authors |
Mina Elahy, Connie Jackaman, John CL Mamo, Virginie Lam, Satvinder S Dhaliwal, Corey Giles, Delia Nelson, Ryusuke Takechi |
| Abstract |
Functional loss of blood-brain barrier (BBB) is suggested to be pivotal to pathogenesis and pathology of vascular-based neurodegenerative disorders such as Alzheimer's disease. We recently reported in wild-type mice maintained on standard diets, progressive deterioration of capillary function with aging concomitant with heightened neuroinflammation. However, the mice used in this study were relatively young (12 months of age) and potential mechanisms for loss of capillary integrity were not investigated per se. The current study therefore extended the previous finding to investigate the effect of aging on BBB integrity in aged mice at 24 months and its potential underlying molecular mechanisms. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 251 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| Portugal | 1 | <1% |
| Argentina | 1 | <1% |
| Unknown | 248 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 60 | 24% |
| Student > Bachelor | 34 | 14% |
| Researcher | 31 | 12% |
| Student > Master | 24 | 10% |
| Student > Doctoral Student | 17 | 7% |
| Other | 30 | 12% |
| Unknown | 55 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 44 | 18% |
| Agricultural and Biological Sciences | 38 | 15% |
| Medicine and Dentistry | 30 | 12% |
| Biochemistry, Genetics and Molecular Biology | 29 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 5% |
| Other | 27 | 11% |
| Unknown | 71 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2022.
All research outputs
#817,877
of 22,794,367 outputs
Outputs from Immunity & Ageing
#21
of 372 outputs
Outputs of similar age
#11,280
of 258,823 outputs
Outputs of similar age from Immunity & Ageing
#1
of 1 outputs
Altmetric has tracked 22,794,367 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 372 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 258,823 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them