Title |
REDHORSE-REcombination and Double crossover detection in Haploid Organisms using next-geneRation SEquencing data
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Published in |
BMC Genomics, February 2015
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DOI | 10.1186/s12864-015-1309-7 |
Pubmed ID | |
Authors |
Jahangheer S Shaik, Asis Khan, Stephen M Beverley, L David Sibley |
Abstract |
Next-generation sequencing technology provides a means to study genetic exchange at a higher resolution than was possible using earlier technologies. However, this improvement presents challenges as the alignments of next generation sequence data to a reference genome cannot be directly used as input to existing detection algorithms, which instead typically use multiple sequence alignments as input. We therefore designed a software suite called REDHORSE that uses genomic alignments, extracts genetic markers, and generates multiple sequence alignments that can be used as input to existing recombination detection algorithms. In addition, REDHORSE implements a custom recombination detection algorithm that makes use of sequence information and genomic positions to accurately detect crossovers. REDHORSE is a portable and platform independent suite that provides efficient analysis of genetic crosses based on Next-generation sequencing data. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 4% |
Unknown | 25 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 31% |
Student > Ph. D. Student | 5 | 19% |
Student > Master | 2 | 8% |
Student > Postgraduate | 2 | 8% |
Professor > Associate Professor | 1 | 4% |
Other | 0 | 0% |
Unknown | 8 | 31% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 8 | 31% |
Biochemistry, Genetics and Molecular Biology | 6 | 23% |
Veterinary Science and Veterinary Medicine | 1 | 4% |
Computer Science | 1 | 4% |
Medicine and Dentistry | 1 | 4% |
Other | 0 | 0% |
Unknown | 9 | 35% |