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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
|
|---|---|
| Published in |
Acta Neuropathologica Communications, January 2015
|
| DOI | 10.1186/s40478-015-0186-2 |
| Pubmed ID | |
| Authors |
Laura J Blair, Haley D Frauen, Bo Zhang, Bryce A Nordhues, Sara Bijan, Yen-Chi Lin, Frank Zamudio, Lidice D Hernandez, Jonathan J Sabbagh, Maj-Linda B Selenica, Chad A Dickey |
| Abstract |
The blood-brain barrier (BBB) is damaged in tauopathies, including progressive supranuclear palsy (PSP) and Alzheimer's disease (AD), which is thought to contribute to pathogenesis later in the disease course. In AD, BBB dysfunction has been associated with amyloid beta (Aß) pathology, but the role of tau in this process is not well characterized. Since increased BBB permeability is found in tauopathies without Aß pathology, like PSP, we suspected that tau accumulation alone could not only be sufficient, but even more important than Aß for BBB damage. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 181 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Portugal | 1 | <1% |
| Unknown | 179 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 43 | 24% |
| Researcher | 25 | 14% |
| Student > Master | 20 | 11% |
| Student > Bachelor | 19 | 10% |
| Student > Doctoral Student | 10 | 6% |
| Other | 20 | 11% |
| Unknown | 44 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 51 | 28% |
| Biochemistry, Genetics and Molecular Biology | 20 | 11% |
| Agricultural and Biological Sciences | 19 | 10% |
| Medicine and Dentistry | 13 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 4% |
| Other | 21 | 12% |
| Unknown | 50 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2019.
All research outputs
#3,446,028
of 25,547,904 outputs
Outputs from Acta Neuropathologica Communications
#673
of 1,584 outputs
Outputs of similar age
#46,830
of 362,504 outputs
Outputs of similar age from Acta Neuropathologica Communications
#3
of 13 outputs
Altmetric has tracked 25,547,904 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,584 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.7. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,504 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.