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Exogenous glycosaminoglycans coat damaged bladder surfaces in experimentally damaged mouse bladder

Overview of attention for article published in BMC Urology, March 2005
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Title
Exogenous glycosaminoglycans coat damaged bladder surfaces in experimentally damaged mouse bladder
Published in
BMC Urology, March 2005
DOI 10.1186/1471-2490-5-4
Pubmed ID
Authors

Kimberly D Kyker, Jean Coffman, Robert E Hurst

Abstract

Interstital cystitis is often treated with exogenous glycosaminoglycans such as heparin, chondroitin sulphate (Uracyst), hyaluronate (Cystistat) or the semi-synthetic pentosan polysulphate (Elmiron). The mechanism of action is presumed to be due to a coating of the bladder surface to replace the normally present chondroitin sulphate and heparan sulphate lost as a result of the disease. This study used fluorescent labelled chondroitin sulphate to track the distribution of glycosaminoglycans administered intravesically to mouse bladder that had been damaged on the surface.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 37%
Student > Ph. D. Student 4 11%
Other 3 9%
Professor > Associate Professor 2 6%
Student > Master 2 6%
Other 1 3%
Unknown 10 29%
Readers by discipline Count As %
Medicine and Dentistry 10 29%
Agricultural and Biological Sciences 6 17%
Engineering 3 9%
Chemistry 3 9%
Earth and Planetary Sciences 1 3%
Other 3 9%
Unknown 9 26%