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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Clinical translation of human neural stem cells
|
|---|---|
| Published in |
Stem Cell Research & Therapy, August 2013
|
| DOI | 10.1186/scrt313 |
| Pubmed ID | |
| Authors |
Ann Tsukamoto, Nobuko Uchida, Alexandra Capela, Thorsten Gorba, Stephen Huhn |
| Abstract |
Human neural stem cell transplants have potential as therapeutic candidates to treat a vast number of disorders of the central nervous system (CNS). StemCells, Inc. has purified human neural stem cells and developed culture conditions for expansion and banking that preserve their unique biological properties. The biological activity of these human central nervous system stem cells (HuCNS-SC®) has been analyzed extensively in vitro and in vivo. When formulated for transplantation, the expanded and cryopreserved banked cells maintain their stem cell phenotype, self-renew and generate mature oligodendrocytes, neurons and astrocytes, cells normally found in the CNS. In this overview, the rationale and supporting data for pursuing neuroprotective strategies and clinical translation in the three components of the CNS (brain, spinal cord and eye) are described. A phase I trial for a rare myelin disorder and phase I/II trial for spinal cord injury are providing intriguing data relevant to the biological properties of neural stem cells, and the early clinical outcomes compel further development. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| United Kingdom | 1 | 1% |
| Unknown | 64 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 16% |
| Researcher | 10 | 15% |
| Student > Ph. D. Student | 10 | 15% |
| Student > Bachelor | 5 | 7% |
| Student > Doctoral Student | 5 | 7% |
| Other | 14 | 21% |
| Unknown | 12 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 22% |
| Neuroscience | 13 | 19% |
| Agricultural and Biological Sciences | 9 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 7% |
| Psychology | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 15 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2023.
All research outputs
#4,082,295
of 23,539,593 outputs
Outputs from Stem Cell Research & Therapy
#378
of 2,488 outputs
Outputs of similar age
#35,373
of 201,603 outputs
Outputs of similar age from Stem Cell Research & Therapy
#2
of 20 outputs
Altmetric has tracked 23,539,593 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,488 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,603 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.