Title |
Transfusion of red cells in hematopoietic stem cell transplantation (TRIST): study protocol for a randomized controlled trial
|
---|---|
Published in |
Trials, September 2011
|
DOI | 10.1186/1745-6215-12-207 |
Pubmed ID | |
Authors |
Jason Tay, Alan Tinmouth, Dean Fergusson, David Allan |
Abstract |
Insight regarding transfusion practices in Hematopoietic Stem cell Transplantation (HSCT) are lacking and the impact of red cell transfusion in this high risk group on outcomes following HSCT are not well appreciated. Red blood cell transfusion can be life-saving, however, liberal use of transfusion in critically ill patients failed to demonstrate significant clinical benefit. A large number of other observational studies have also demonstrated an association between red blood cell transfusions and increased morbidity such as infections and multi organ failure as well as increased mortality. The role of red cell transfusion on the clinical outcomes observed in patients undergoing HSCT remains poorly understood and a prospective randomized study of transfusion is required to gain insight and knowledge on best transfusion practices in this high risk population. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
Switzerland | 1 | 2% |
Unknown | 58 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 15% |
Student > Master | 8 | 13% |
Other | 7 | 11% |
Student > Ph. D. Student | 4 | 7% |
Student > Postgraduate | 4 | 7% |
Other | 12 | 20% |
Unknown | 17 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 46% |
Nursing and Health Professions | 4 | 7% |
Psychology | 2 | 3% |
Agricultural and Biological Sciences | 2 | 3% |
Business, Management and Accounting | 1 | 2% |
Other | 6 | 10% |
Unknown | 18 | 30% |