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Evidence of more ion channels inhibited by celecoxib: KV1.3 and L-type Ca2+ channels

Overview of attention for article published in BMC Research Notes, January 2015
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Title
Evidence of more ion channels inhibited by celecoxib: KV1.3 and L-type Ca2+ channels
Published in
BMC Research Notes, January 2015
DOI 10.1186/s13104-015-1023-1
Pubmed ID
Authors

Roman V Frolov, Satpal Singh

Abstract

Celecoxib, a selective inhibitor of cyclooxygenase-2, can directly modulate many voltage-activated potassium, sodium and calcium channels and alter functioning of excitable cells. The inhibitory and facilitating effects of celecoxib on ion channels occur at low micromolar concentrations, bordering on therapeutic concentrations achievable in the clinical setting. The experiments described here were performed with the goals (1) to increase the range of ion channels tested, and (2) to examine possible differences in celecoxib's effects on channels from different species.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 1 17%
Student > Ph. D. Student 1 17%
Professor > Associate Professor 1 17%
Researcher 1 17%
Student > Master 1 17%
Other 0 0%
Unknown 1 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 33%
Pharmacology, Toxicology and Pharmaceutical Science 1 17%
Unspecified 1 17%
Social Sciences 1 17%
Unknown 1 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2015.
All research outputs
#3,417,381
of 5,174,102 outputs
Outputs from BMC Research Notes
#1,035
of 1,641 outputs
Outputs of similar age
#106,250
of 158,707 outputs
Outputs of similar age from BMC Research Notes
#34
of 44 outputs
Altmetric has tracked 5,174,102 research outputs across all sources so far. This one is in the 29th percentile – i.e., 29% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,641 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 158,707 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.