Title |
Interleukin-10 and soil-transmitted helminth infections in Honduran children
|
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Published in |
BMC Research Notes, January 2015
|
DOI | 10.1186/s13104-015-1019-x |
Pubmed ID | |
Authors |
Ana Sanchez, Dylan Mahoney, José Gabrie |
Abstract |
Soil-transmitted helminths (STH) establish chronic infections in the human intestine. The host reacts to these infections with a dominant T-helper type 2 cell (Th2) response that while attempting to control the worm population, can also provide an anti-inflammatory environment favourable for parasite survival. Regulatory cytokine interleukin 10 (IL-10) has been proposed as a key molecule involved in the attenuation of chronic inflammation and the ensuing tolerance for these helminth parasites. The objective of this study was to determine whether STH-infected children from an endemic community had increased circulating IL-10 levels when compared to non-infected children. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 2% |
Unknown | 61 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 18% |
Student > Bachelor | 9 | 15% |
Student > Doctoral Student | 6 | 10% |
Researcher | 5 | 8% |
Lecturer | 4 | 6% |
Other | 14 | 23% |
Unknown | 13 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 26% |
Agricultural and Biological Sciences | 12 | 19% |
Biochemistry, Genetics and Molecular Biology | 7 | 11% |
Immunology and Microbiology | 5 | 8% |
Nursing and Health Professions | 2 | 3% |
Other | 7 | 11% |
Unknown | 13 | 21% |