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Recurrent CYP2C19 deletion allele is associated with triple-negative breast cancer

Overview of attention for article published in BMC Cancer, December 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

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1 patent
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1 Facebook page

Citations

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18 Dimensions

Readers on

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24 Mendeley
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Title
Recurrent CYP2C19 deletion allele is associated with triple-negative breast cancer
Published in
BMC Cancer, December 2014
DOI 10.1186/1471-2407-14-902
Pubmed ID
Authors

Anna Tervasmäki, Robert Winqvist, Arja Jukkola-Vuorinen, Katri Pylkäs

Abstract

Using a genome-wide approach, we have previously observed an increase in the frequency of rare copy number variants (CNVs) in familial and early-onset breast cancer cases when compared to controls. Moreover, the biological networks of the CNV disrupted genes differed between the two groups. Here, six of the previously observed CNVs were selected for further investigation. Four of these were singletons and disturbed the following genes: DCLRE1C, CASP3, DAB2IP and ITGA9, encoding proteins that are part of the TP53 and β-estradiol centered network. The two others were recurrent alleles and disrupted CDH19 and CYP2C19 genes. Of these, CDH19 encodes a cadherin functioning as a cell-cell adhesion receptor and CYP2C19 a CYP450 enzyme with a major function in estrogen catabolism.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Pakistan 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 25%
Student > Master 4 17%
Professor > Associate Professor 2 8%
Student > Doctoral Student 1 4%
Student > Bachelor 1 4%
Other 4 17%
Unknown 6 25%
Readers by discipline Count As %
Medicine and Dentistry 6 25%
Agricultural and Biological Sciences 5 21%
Biochemistry, Genetics and Molecular Biology 4 17%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Unknown 7 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2021.
All research outputs
#7,212,132
of 22,796,179 outputs
Outputs from BMC Cancer
#1,944
of 8,295 outputs
Outputs of similar age
#102,478
of 361,382 outputs
Outputs of similar age from BMC Cancer
#44
of 164 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 8,295 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,382 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 164 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.