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Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice

Overview of attention for article published in Neural Development, May 2014
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Title
Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice
Published in
Neural Development, May 2014
DOI 10.1186/1749-8104-9-11
Pubmed ID
Authors

Punita Bhansali, Ilana Rayport, Alexandra Rebsam, Carol Mason

Abstract

Proper binocular vision depends on the routing at the optic chiasm of the correct proportion of retinal ganglion cell (RGC) axons that project to the same (ipsilateral) and opposite (contralateral) side of the brain. The ipsilateral RGC projection is reduced in mammals with albinism, a congenital disorder characterized by deficient pigmentation in the skin, hair, and eyes. Compared to the pigmented embryonic mouse retina, the albino embryonic mouse retina has fewer RGCs that express the zinc-finger transcription factor, Zic2, which is transiently expressed by RGCs fated to project ipsilaterally. Here, using Zic2 as a marker of ipsilateral RGCs, Islet2 as a marker of contralateral RGCs, and birthdating, we investigate spatiotemporal dynamics of RGC production as they relate to the phenotype of diminished ipsilateral RGC number in the albino retina.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 23%
Student > Ph. D. Student 7 20%
Student > Bachelor 6 17%
Student > Master 5 14%
Professor 1 3%
Other 1 3%
Unknown 7 20%
Readers by discipline Count As %
Neuroscience 13 37%
Agricultural and Biological Sciences 6 17%
Biochemistry, Genetics and Molecular Biology 5 14%
Medicine and Dentistry 1 3%
Veterinary Science and Veterinary Medicine 1 3%
Other 2 6%
Unknown 7 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2014.
All research outputs
#20,265,771
of 22,796,179 outputs
Outputs from Neural Development
#206
of 226 outputs
Outputs of similar age
#192,903
of 227,430 outputs
Outputs of similar age from Neural Development
#5
of 6 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 226 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,430 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
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