Title |
Risk factors of renal dysfunction and their interaction in level-low lead exposure paint workers
|
---|---|
Published in |
BMC Public Health, April 2018
|
DOI | 10.1186/s12889-018-5475-9 |
Pubmed ID | |
Authors |
Xiaojuan Wang, Huiling Liang, Yan Wang, Chang Cai, Jimeng Li, Xun Li, Mian Wang, Mengshi Chen, Xin Xu, Hongzhuan Tan |
Abstract |
To explore the effect of low-level lead exposure on renal dysfunction in paint works, and analyze the interaction between low-level lead exposure and other influence factors of renal dysfunction. Seven hundred forty seven workers from Sany Heavy Industry Company and Xiangjiang Kansai Paint Company who have been exposed to paint were chosen by random cluster sampling. Their blood lead level and Urine β2-micro globulin level (renal dysfunction) were tested,risk factors of renal dysfunction in paint workers and their interactions were analyzed. The prevalence of renal dysfunction was 12.37%. Risk factors of renal dysfunction in paint workers mainly included longer working years (OR = 1.699, 95% CI: 1.226~ 2.355), blood lead positive (OR = 2.847, 95% CI: 1.577~ 5.139) and hypertension (OR = 2.192, 95% CI: 1.103~ 4.359). Positive interaction existed between hypertension and low-level blood lead on renal dysfunction in paint workers, the RERI (Relative excess risk of interaction), API (Attributable proportions of interaction) and S(the synergy index) were 4.758, 54.5% and 2.604 respectively. Low-level lead exposure and hypertension not only have independent effect on renal dysfunction in paint workers, but also had obvious positive interaction in paint workers. Interventions aimed at blood lead and blood pressure at the same time will better prenvent from renal dysfunction. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 21% |
Student > Master | 2 | 6% |
Lecturer > Senior Lecturer | 2 | 6% |
Student > Doctoral Student | 2 | 6% |
Student > Postgraduate | 2 | 6% |
Other | 5 | 15% |
Unknown | 14 | 41% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 21% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Nursing and Health Professions | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Unspecified | 1 | 3% |
Other | 5 | 15% |
Unknown | 15 | 44% |