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Use of vancomycin as a surrogate for dalbavancin in vitro susceptibility testing: results from the DISCOVER studies

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, April 2015
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Title
Use of vancomycin as a surrogate for dalbavancin in vitro susceptibility testing: results from the DISCOVER studies
Published in
Annals of Clinical Microbiology and Antimicrobials, April 2015
DOI 10.1186/s12941-015-0081-5
Pubmed ID
Authors

Michael W Dunne, Dan Sahm, Sailaja Puttagunta

Abstract

Dalbavancin is a lipoglycopepetide antibiotic with activity against gram positive pathogens recently approved for treatment of acute bacterial skin and skin structure infections. Pending the introduction of antimicrobial susceptibility tests, we examined the utility of vancomycin inhibitory concentrations to predict dalbavancin susceptibility in a panel of isolates obtained from phase 3 registration studies. 99.6% of Staphylococcus aureus and 99.0% of beta-hemolytic streptococci which are susceptible to vancomycin will have an MIC at or below the US FDA susceptibility breakpoint for dalbavancin. Vancomycin should be considered as a surrogate for in vitro dalbavancin susceptibility testing.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 17%
Researcher 4 17%
Student > Ph. D. Student 4 17%
Student > Postgraduate 2 8%
Student > Bachelor 2 8%
Other 3 13%
Unknown 5 21%
Readers by discipline Count As %
Medicine and Dentistry 7 29%
Pharmacology, Toxicology and Pharmaceutical Science 5 21%
Immunology and Microbiology 3 13%
Agricultural and Biological Sciences 2 8%
Environmental Science 1 4%
Other 1 4%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2016.
All research outputs
#17,752,946
of 22,797,621 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#395
of 607 outputs
Outputs of similar age
#180,388
of 263,845 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#7
of 13 outputs
Altmetric has tracked 22,797,621 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 607 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,845 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.