Title |
Subversion of the B-cell compartment during parasitic, bacterial, and viral infections
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Published in |
BMC Immunology, March 2015
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DOI | 10.1186/s12865-015-0079-y |
Pubmed ID | |
Authors |
Gwenoline Borhis, Yolande Richard |
Abstract |
Recent studies on HIV infection have identified new human B-cell subsets with a potentially important impact on anti-viral immunity. Current work highlights the occurrence of similar B-cell alterations in other viral, bacterial, and parasitic infections, suggesting that common strategies have been developed by pathogens to counteract protective immunity. For this review, we have selected key examples of human infections for which B-cell alterations have been described, to highlight the similarities and differences in the immune responses to a variety of pathogens. We believe that further comparisons between these models will lead to critical progress in the understanding of B-cell mechanisms and will open new target avenues for therapeutic interventions. |
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Ecuador | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
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Mendeley readers
Geographical breakdown
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Unknown | 58 | 97% |
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Researcher | 10 | 17% |
Student > Master | 9 | 15% |
Student > Doctoral Student | 3 | 5% |
Student > Bachelor | 3 | 5% |
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