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Important prognostic factors for survival in patients with malignant pleural effusion

Overview of attention for article published in BMC Pulmonary Medicine, March 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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1 news outlet
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4 X users
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1 Facebook page

Citations

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89 Dimensions

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122 Mendeley
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Title
Important prognostic factors for survival in patients with malignant pleural effusion
Published in
BMC Pulmonary Medicine, March 2015
DOI 10.1186/s12890-015-0025-z
Pubmed ID
Authors

Mauro Musa Zamboni, Cyro Teixeira da Silva, Rodrigo Baretta, Edson Toscano Cunha, Gilberto Perez Cardoso

Abstract

The approach to palliative treatment of malignant pleural effusion (MPE) should be individualized because these patients generally have poor survival. Our study aimed to develop a model to identify prognostic factors or survival time in patients diagnosed with MPE. This is a retrospective, descriptive, observational study to identify prognostic factors related to MPE in patients with a confirmed cancer diagnosis. Cox regression analysis was used to determine significant potential prognostic factors with respect to survival time. Survival time was defined as the time from pathological diagnosis to death. One hundred and sixty-five patients were included; 77 were men (47%) and 88 were women (53%). The median age was 60 years, and all of the patients were pathologically proven to have MPE. Non-small-cell lung cancer (36.0%), breast carcinoma (26%), and lymphoma (13.0%) were the most frequently diagnosed tumors. The median overall survival of patients from the initial diagnosis was 5 months (range: 1.0-96.0 months). Kaplan-Meier univariate analysis showed that survival was significantly related to the following prognostic factors: ECOG PS (hazard ratio [HR] 10.0, 95% confidence interval [95% CI] 5.96 to 18.50, p < 0.0001), primary cancer site (HR 1.99, 95% CI 1.23 to 3.22, p < 0.01), positive pleural cytology (HR 1.25, 95% CI 0.88 to 1.78, p = 0.04), and positive histology (HR 1.33, 95% CI 0.97 to 1.81, p = 0.04). Other potential independent diagnostic factors that were examined did not affect survival. Cox regression analysis showed that only the ECOG PS was highly predictive of survival (HR 73.58, 95% CI 23.44 to 230.95, p < 0.0001). ECOG PS is an independent predictor of survival in patients with MPE at initial diagnosis. This prognostic factor can help physicians select patients for appropriate palliative treatment of this syndrome.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
Unknown 121 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 13%
Student > Postgraduate 14 11%
Student > Ph. D. Student 11 9%
Student > Bachelor 9 7%
Other 8 7%
Other 22 18%
Unknown 42 34%
Readers by discipline Count As %
Medicine and Dentistry 60 49%
Nursing and Health Professions 6 5%
Biochemistry, Genetics and Molecular Biology 5 4%
Agricultural and Biological Sciences 3 2%
Unspecified 1 <1%
Other 4 3%
Unknown 43 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2017.
All research outputs
#2,575,304
of 22,799,071 outputs
Outputs from BMC Pulmonary Medicine
#147
of 1,910 outputs
Outputs of similar age
#34,891
of 263,900 outputs
Outputs of similar age from BMC Pulmonary Medicine
#5
of 44 outputs
Altmetric has tracked 22,799,071 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,910 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,900 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.