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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effects of n-3 fatty acids and exercise on oxidative stress parameters in type 2 diabetic: a randomized clinical trial
|
|---|---|
| Published in |
Journal of the International Society of Sports Nutrition, April 2022
|
| DOI | 10.1186/s12970-018-0222-2 |
| Pubmed ID | |
| Authors |
Ana Paula Trussardi Fayh, Katiuce Borges, Giovani Santos Cunha, Mauricio Krause, Ricardo Rocha, Paulo Ivo Homem de Bittencourt, José Cláudio Fonseca Moreira, Rogério Friedman, Juliane da Silva Rossato, Jõao Roberto Fernandes, Alvaro Reischak-Oliveira |
| Abstract |
The relationship between diabetes and oxidative stress has been previously reported. Exercise represents a useful non-pharmacological strategy for the treatment in type 2 diabetic (T2DM) patients, but high intensity exercise can induce a transient inflammatory state and increase oxidative stress. Nutritional strategies that may contribute to the reduction of oxidative stress induced by acute exercise are necessary. The aim of this study was to examine if n-3 PUFA supplementation intervention can attenuate the inflammatory response and oxidative stress associated with high intensity exercise in this population. As a primary outcome, lipoperoxidation measurements (TBARS and F2-isoprostanes) were selected. Thirty T2DM patients, without chronic complications, were randomly allocated into two groups: placebo (gelatin capsules) or n-3 PUFA (capsules containing 180 mg of eicosapentaenoic acid and 120 mg of docosahexaenoic acid). Blood samples were collected fasting before and after 8 weeks supplementation. In the beginning and at the end of protocol, an acute exercise was performed (treadmill), and new blood samples were collected before and immediately after the exercise for measurements of oxidative stress and high-sensitivity C-reactive protein (hs-CRP). After the supplementation period, a decrease in triglycerides levels was observed only in n-3 PUFA supplementation group (mean difference and 95% CI of 0.002 (0.000-0.004), p = 0.005). Supplementation also significantly reduced TRAP levels after exercise (mean difference and 95% CI to 9641 (- 20,068-39,351) for - 33,884 (- 56,976 - -10,793), p = 0.004, Cohen's d effect size = 1.12), but no significant difference was observed in n-3 PUFA supplementation group in lipoperoxidation parameters as TBARS (mean difference and 95% CI to - 3.8 (- 10-2.4) for - 2.9 (- 1.6-7.4) or F2-isoprostanes (mean difference and 95% CI -0.05 (- 0.19-0.10) for - 0.02 (- 0.19-0.16), p > 0.05 for both. PUFA n-3 supplementation reduced triglycerides as well as TRAP levels after exercise, without a significant effect on inflammatory and oxidative stress markers.This study is registered at ClinicalTrials.gov with the registration number of NCT03182712. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 171 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 171 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 25 | 15% |
| Student > Master | 22 | 13% |
| Student > Ph. D. Student | 15 | 9% |
| Researcher | 12 | 7% |
| Other | 6 | 4% |
| Other | 28 | 16% |
| Unknown | 63 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 27 | 16% |
| Medicine and Dentistry | 21 | 12% |
| Sports and Recreations | 18 | 11% |
| Agricultural and Biological Sciences | 12 | 7% |
| Biochemistry, Genetics and Molecular Biology | 10 | 6% |
| Other | 12 | 7% |
| Unknown | 71 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2018.
All research outputs
#14,981,465
of 23,045,021 outputs
Outputs from Journal of the International Society of Sports Nutrition
#768
of 887 outputs
Outputs of similar age
#232,101
of 440,499 outputs
Outputs of similar age from Journal of the International Society of Sports Nutrition
#734
of 851 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 887 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 58.5. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 851 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.