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PRNP genetic variability and molecular typing of natural goat scrapie isolates in a high number of infected flocks

Overview of attention for article published in Veterinary Research, September 2011
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Title
PRNP genetic variability and molecular typing of natural goat scrapie isolates in a high number of infected flocks
Published in
Veterinary Research, September 2011
DOI 10.1186/1297-9716-42-104
Pubmed ID
Authors

Eirini G Fragkiadaki, Gabriele Vaccari, Loukia V Ekateriniadou, Umberto Agrimi, Nektarios D Giadinis, Barbara Chiappini, Elena Esposito, Michela Conte, Romolo Nonno

Abstract

One hundred and four scrapie positive and 77 negative goats from 34 Greek mixed flocks were analysed by prion protein gene sequencing and 17 caprine scrapie isolates from 11 flocks were submitted to molecular isolate typing. For the first time, the protective S146 variant was reported in Greece, while the protective K222 variant was detected in negative but also in five scrapie positive goats from heavily infected flocks. By immunoblotting six isolates, including two goat flockmates carrying the K222 variant, showed molecular features slightly different from all other Greek and Italian isolates co-analysed, possibly suggesting the presence of different scrapie strains in Greece.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 29%
Student > Ph. D. Student 4 19%
Student > Doctoral Student 2 10%
Student > Bachelor 2 10%
Professor > Associate Professor 2 10%
Other 3 14%
Unknown 2 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 48%
Biochemistry, Genetics and Molecular Biology 4 19%
Medicine and Dentistry 3 14%
Immunology and Microbiology 1 5%
Veterinary Science and Veterinary Medicine 1 5%
Other 0 0%
Unknown 2 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2011.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Veterinary Research
#1,035
of 1,337 outputs
Outputs of similar age
#119,829
of 143,260 outputs
Outputs of similar age from Veterinary Research
#7
of 12 outputs
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