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Cardiovascular disease and arsenic exposure in Inner Mongolia, China: a case control study

Overview of attention for article published in Environmental Health, April 2015
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Title
Cardiovascular disease and arsenic exposure in Inner Mongolia, China: a case control study
Published in
Environmental Health, April 2015
DOI 10.1186/s12940-015-0022-y
Pubmed ID
Authors

Timothy J Wade, Yajuan Xia, Judy Mumford, Kegong Wu, X Chris Le, Elizabeth Sams, William E Sanders

Abstract

Millions of people are at risk from the adverse effects of arsenic exposure through drinking water. Increasingly, non-cancer effects such as cardiovascular disease have been associated with drinking water arsenic exposures. However, most studies have been conducted in highly exposed populations and lacked individual measurements. To evaluate the association between cardiovascular disease and well-water arsenic exposure. We conducted a hospital based case control study in Inner Mongolia, China. Cases and controls were prospectively identified and enrolled from a large hospital in the Hangjin Hou area. Cases were patients diagnosed with cardiovascular disease and controls were patients free from cardiovascular disease, admitted for conditions unrelated to arsenic exposure. Water from the primary water source and toenail samples were collected from each subject and tested for inorganic arsenic. Arsenic exposures were moderate with mean and median arsenic exposures of 8.9 μg/L and 13.1 μg/L, respectively. A total of 298 cases and 275 controls were enrolled. The adjusted odds ratio (AOR) and corresponding 95% confidence interval (95% CI) for a 10 μg/L increase in water arsenic were 1.19 (95% CI: 1.03, 1.38). Compared to exposures less than 10 μg/L, the AOR for water arsenic exposures above 40 μg/L was 4.05 (95% CI: 1.1-14.99, p = 0.04). Nail arsenic above 1.38 μg/g was also associated with an increased risk of cardiovascular disease. By using standardized case definitions and collecting individual measurements of arsenic, this study addressed several limitations of previous studies. The results provide further evidence of the association between cardiovascular disease and arsenic at moderate exposures.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 19%
Student > Ph. D. Student 9 14%
Student > Bachelor 8 13%
Researcher 8 13%
Professor 4 6%
Other 10 16%
Unknown 13 20%
Readers by discipline Count As %
Medicine and Dentistry 15 23%
Agricultural and Biological Sciences 5 8%
Environmental Science 5 8%
Biochemistry, Genetics and Molecular Biology 4 6%
Chemistry 4 6%
Other 15 23%
Unknown 16 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2015.
All research outputs
#17,753,591
of 22,799,071 outputs
Outputs from Environmental Health
#1,205
of 1,488 outputs
Outputs of similar age
#180,698
of 264,665 outputs
Outputs of similar age from Environmental Health
#26
of 28 outputs
Altmetric has tracked 22,799,071 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,488 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.3. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,665 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.