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REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies

Overview of attention for article published in BMC Bioinformatics, April 2015
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Title
REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies
Published in
BMC Bioinformatics, April 2015
DOI 10.1186/s12859-015-0552-x
Pubmed ID
Authors

Kai Wang, Hiroki Nishida

Abstract

Genes encoding transcription factors that constitute gene-regulatory networks and maternal factors accumulating in egg cytoplasm are two classes of essential genes that play crucial roles in developmental processes. Transcription factors control the expression of their downstream target genes by interacting with cis-regulatory elements. Maternal factors initiate embryonic developmental programs by regulating the expression of zygotic genes and various other events during early embryogenesis. This article documents the transcription factors of 77 metazoan species as well as human and mouse maternal factors. We improved the previous method using a statistical approach adding Gene Ontology information to Pfam based identification of transcription factors. This method detects previously un-discovered transcription factors. The novel features of this database are: (1) It includes both transcription factors and maternal factors, although the number of species, in which maternal factors are listed, is limited at the moment. (2) Ontological representation at the cell, tissue, organ, and system levels has been specially designed to facilitate development studies. This is the unique feature in our database and is not available in other transcription factor databases. A user-friendly web interface, REGULATOR ( http://www.bioinformatics.org/regulator/ ), which can help researchers to efficiently identify, validate, and visualize the data analyzed in this study, are provided. Using this web interface, users can browse, search, and download detailed information on species of interest, genes, transcription factor families, or developmental ontology terms.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 3%
Brazil 1 3%
Unknown 32 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 35%
Student > Bachelor 5 15%
Student > Ph. D. Student 5 15%
Other 2 6%
Professor 2 6%
Other 4 12%
Unknown 4 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 44%
Biochemistry, Genetics and Molecular Biology 8 24%
Computer Science 5 15%
Engineering 2 6%
Unknown 4 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2015.
All research outputs
#15,481,064
of 24,990,015 outputs
Outputs from BMC Bioinformatics
#4,702
of 7,629 outputs
Outputs of similar age
#140,934
of 269,756 outputs
Outputs of similar age from BMC Bioinformatics
#85
of 132 outputs
Altmetric has tracked 24,990,015 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,629 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,756 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 132 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.