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Effect of desmopressin administration on intraoperative blood loss and quality of the surgical field during functional endoscopic sinus surgery: a randomized, clinical trial

Overview of attention for article published in BMC Anesthesiology, April 2015
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Title
Effect of desmopressin administration on intraoperative blood loss and quality of the surgical field during functional endoscopic sinus surgery: a randomized, clinical trial
Published in
BMC Anesthesiology, April 2015
DOI 10.1186/s12871-015-0034-8
Pubmed ID
Authors

Hua Shao, Li-Ting Kuang, Wei-Jian Hou, Tao Zhang

Abstract

Bleeding during functional endoscopic sinus surgery is a challenge for the quality of the surgical field for surgeons. This study aimed to evaluate the effect of desmopressin premedication on blood loss and the quality of the surgical field in endoscopic sinus surgery. A total of 90 American Society of Anesthesiologists physical status I-II patients underwent endoscopic sinus surgery for chronic sinusitis. They were randomly allocated to receive either desmopressin 0.3 μg/kg or saline before the operation. Management of anesthesia was achieved with propofol and remifentanil infusions, with moderate, controlled hypotension. Blood loss and quality of the surgical field were assessed after surgery. Effects of desmopressin on anesthetic requirements and hemodynamic variables were analyzed. Blood loss was significantly less in the desmopressin group (mean ± SD, 42 ± 8.7 ml) than in the control group (70 ± 9.2 ml, P < 0.001). Surgeons were more satisfied with the surgical field in the desmopressin group than in the control group (median score, 4 [3-5] vs. 7 [6-9], P < 0.001). Requirements for remifentanil and esmolol were lower in the desmopressin group than in the control group. Premedication with desmopressin 0.3 μg/kg can effectively reduce bleeding during endoscopic sinus surgery.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 19%
Student > Postgraduate 4 15%
Researcher 3 11%
Student > Bachelor 2 7%
Student > Doctoral Student 2 7%
Other 4 15%
Unknown 7 26%
Readers by discipline Count As %
Medicine and Dentistry 15 56%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Environmental Science 1 4%
Unspecified 1 4%
Agricultural and Biological Sciences 1 4%
Other 1 4%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2016.
All research outputs
#20,268,102
of 22,799,071 outputs
Outputs from BMC Anesthesiology
#1,174
of 1,496 outputs
Outputs of similar age
#223,654
of 264,854 outputs
Outputs of similar age from BMC Anesthesiology
#35
of 37 outputs
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