↓ Skip to main content

Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, September 2011
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
30 Dimensions

Readers on

mendeley
38 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells
Published in
Journal of Experimental & Clinical Cancer Research, September 2011
DOI 10.1186/1756-9966-30-82
Pubmed ID
Authors

Jingyan Sun, Jinpu Yu, Hui Li, Lili Yang, Feng Wei, Wenwen Yu, Juntian Liu, Xiubao Ren

Abstract

The inflammatory enzyme indoleamine 2, 3-dioxygenase (IDO) participates in immune tolerance and promotes immune escape of IDO+ tumors. A recent hypothesis suggested that IDO may contribute to the differentiation of new T regulatory cells (Tregs) from naive CD4+ T cells. In this study we investigated the role of IDO in induction of immunosuppression in breast cancer by increasing the apoptosis of T cells and the proportion of Tregs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Netherlands 1 3%
Korea, Republic of 1 3%
Italy 1 3%
United States 1 3%
Unknown 33 87%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 29%
Student > Master 7 18%
Researcher 6 16%
Student > Bachelor 3 8%
Lecturer > Senior Lecturer 2 5%
Other 8 21%
Unknown 1 3%
Readers by discipline Count As %
Medicine and Dentistry 11 29%
Agricultural and Biological Sciences 9 24%
Biochemistry, Genetics and Molecular Biology 5 13%
Engineering 3 8%
Immunology and Microbiology 3 8%
Other 4 11%
Unknown 3 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2011.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#1,636
of 2,379 outputs
Outputs of similar age
#114,578
of 137,124 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#12
of 16 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,379 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 137,124 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.