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Mendeley readers
Attention Score in Context
| Title |
A depauperate immune repertoire precedes evolution of sociality in bees
|
|---|---|
| Published in |
Genome Biology, April 2015
|
| DOI | 10.1186/s13059-015-0628-y |
| Pubmed ID | |
| Authors |
Seth M Barribeau, Ben M Sadd, Louis du Plessis, Mark JF Brown, Severine D Buechel, Kaat Cappelle, James C Carolan, Olivier Christiaens, Thomas J Colgan, Silvio Erler, Jay Evans, Sophie Helbing, Elke Karaus, H Michael G Lattorff, Monika Marxer, Ivan Meeus, Kathrin Näpflin, Jinzhi Niu, Regula Schmid-Hempel, Guy Smagghe, Robert M Waterhouse, Na Yu, Evgeny M Zdobnov, Paul Schmid-Hempel |
| Abstract |
Sociality has many rewards, but can also be dangerous, as high population density and low genetic diversity, common in social insects, is ideal for parasite transmission. Despite this risk, honeybees and other sequenced social insects have far fewer canonical immune genes relative to solitary insects. Social protection from infection, including behavioral responses, may explain this depauperate immune repertoire. Here, based on full genome sequences, we describe the immune repertoire of two ecologically and commercially important bumblebee species that diverged approximately 18 million years ago, the North American Bombus impatiens and European Bombus terrestris. We find that the immune systems of these bumblebees, two species of honeybee, and a solitary leafcutting bee, are strikingly similar. Transcriptional assays confirm the expression of many of these genes in an immunological context and more strongly in young queens than males, affirming Bateman's principle of greater investment in female immunity. We find evidence of positive selection in genes encoding antiviral responses, components of the Toll and JAK/STAT pathways, and serine protease inhibitors in both social and solitary bees. Finally, we detect many genes across pathways that differ in selection between bumblebees and honeybees, or between the social and solitary clades. The similarity in immune complement across a gradient of sociality suggests that a reduced immune repertoire predates the evolution of sociality in bees. The differences in selection on immune genes likely reflect divergent pressures exerted by parasites across social contexts. |
X Demographics
The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 35% |
| Canada | 3 | 8% |
| United Kingdom | 2 | 5% |
| Mexico | 1 | 3% |
| Germany | 1 | 3% |
| Norway | 1 | 3% |
| Finland | 1 | 3% |
| Unknown | 15 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 59% |
| Scientists | 11 | 30% |
| Science communicators (journalists, bloggers, editors) | 3 | 8% |
| Unknown | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 228 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| United Kingdom | 2 | <1% |
| Germany | 1 | <1% |
| Taiwan | 1 | <1% |
| New Zealand | 1 | <1% |
| Unknown | 220 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 60 | 26% |
| Researcher | 38 | 17% |
| Student > Master | 23 | 10% |
| Student > Doctoral Student | 20 | 9% |
| Student > Bachelor | 18 | 8% |
| Other | 37 | 16% |
| Unknown | 32 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 126 | 55% |
| Biochemistry, Genetics and Molecular Biology | 33 | 14% |
| Veterinary Science and Veterinary Medicine | 3 | 1% |
| Immunology and Microbiology | 3 | 1% |
| Unspecified | 3 | 1% |
| Other | 15 | 7% |
| Unknown | 45 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 117. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2023.
All research outputs
#361,723
of 25,530,891 outputs
Outputs from Genome Biology
#170
of 4,486 outputs
Outputs of similar age
#3,936
of 280,057 outputs
Outputs of similar age from Genome Biology
#4
of 69 outputs
Altmetric has tracked 25,530,891 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,486 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,057 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.