Title |
Quality assessment of tandem mass spectra using support vector machine (SVM)
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Published in |
BMC Bioinformatics, January 2009
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DOI | 10.1186/1471-2105-10-s1-s49 |
Pubmed ID | |
Authors |
An-Min Zou, Fang-Xiang Wu, Jia-Rui Ding, Guy G Poirier |
Abstract |
Tandem mass spectrometry has become particularly useful for the rapid identification and characterization of protein components of complex biological mixtures. Powerful database search methods have been developed for the peptide identification, such as SEQUEST and MASCOT, which are implemented by comparing the mass spectra obtained from unknown proteins or peptides with theoretically predicted spectra derived from protein databases. However, the majority of spectra generated from a mass spectrometry experiment are of too poor quality to be interpreted while some of spectra with high quality cannot be interpreted by one method but perhaps by others. Hence a filtering algorithm that removes those spectra with poor quality prior to the database search is appealing. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 1 | 4% |
Other | 4 | 17% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Unspecified | 1 | 4% |
Other | 3 | 13% |
Unknown | 2 | 9% |