Title |
Detecting individual ancestry in the human genome
|
---|---|
Published in |
Investigative Genetics, May 2015
|
DOI | 10.1186/s13323-015-0019-x |
Pubmed ID | |
Authors |
Andreas Wollstein, Oscar Lao |
Abstract |
Detecting and quantifying the population substructure present in a sample of individuals are of main interest in the fields of genetic epidemiology, population genetics, and forensics among others. To date, several algorithms have been proposed for estimating the amount of genetic ancestry within an individual. In the present review, we introduce the most widely used methods in population genetics for detecting individual genetic ancestry. We further show, by means of simulations, the performance of popular algorithms for detecting individual ancestry in various controlled demographic scenarios. Finally, we provide some hints on how to interpret the results from these algorithms. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 27% |
United States | 3 | 20% |
Australia | 1 | 7% |
Unknown | 7 | 47% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 53% |
Scientists | 6 | 40% |
Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | <1% |
Sweden | 1 | <1% |
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Poland | 1 | <1% |
Unknown | 98 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 29 | 28% |
Researcher | 19 | 18% |
Student > Master | 14 | 14% |
Student > Bachelor | 12 | 12% |
Professor > Associate Professor | 6 | 6% |
Other | 14 | 14% |
Unknown | 9 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 44 | 43% |
Biochemistry, Genetics and Molecular Biology | 25 | 24% |
Computer Science | 6 | 6% |
Environmental Science | 3 | 3% |
Medicine and Dentistry | 3 | 3% |
Other | 11 | 11% |
Unknown | 11 | 11% |